ANTI-BAALC ANTIBODY

Analysis Note

ControlMouse brain tissue lysate

Application

Research CategoryNeuroscience

Research Sub CategoryDevelopmental Signaling

Detect Brain & acute leukemia cytoplasmic protein using this rabbit polyclonal antibody, Anti-BAALC Antibody validated for use in western blotting.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Brain and acute leukemia cytoplasmic protein (BAALC) interacts with CAMK2A in a synaptic role at postsynaptic lipid rafts. BAALC is expressed by neural, hematopoietic, normal early progenitor cells and in the most immature type of blasts in acute leukemia. Isoform 2 and isoform 6 are also expressed in the brain.

Immunogen

KLH-conjugated linear peptide corresponding to the CAMK2A interaction domain of human BAALC.

Epitope: CAMK2A interaction domain

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Antigen Affinity Purified

Quality

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected BAALC in 10 µg of mouse brain tissue lysate.

Specificity

This antibody recognizes the CAMK2A interaction domain of BAALC. This antibody should recognize all isoforms in uniprot.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~22 kDa observed. Uniprot describes 6 isoforms produced by alternative splicing at ~19 kDa, ~16 kDa, ~9 kDa, ~8 kDa and ~6 kDa